BRD1 Protein (AA 556-688) (His tag,DYKDDDDK Tag)
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- Target See all BRD1 Proteins
- BRD1 (Bromodomain Containing 1 (BRD1))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 556-688
- Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This BRD1 protein is labelled with His tag,DYKDDDDK Tag.
- Application
- Binding Studies (Bind), Screening Assay (ScA)
- Characteristics
- The peptide corresponding to amino acids 556-688 that contains the bromodomain sequences of BRD1 (accession number NP_055392.1) was expressed in E. coli and contains an N-terminal His tag and C-terminal FLAG tag with an observed molecular weight of 21.5 kDa.
- Top Product
- Discover our top product BRD1 Protein
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- Application Notes
- Recombinant BRD1 (556-688) is suitable for use in binding assays, inhibitor screening, and selectivity profiling.
- Restrictions
- For Research Use only
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- Handling Advice
- Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
- Storage
- -80 °C
- Storage Comment
- Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation.
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- Target
- BRD1 (Bromodomain Containing 1 (BRD1))
- Alternative Name
- BRD1 (BRD1 Products)
- Synonyms
- BDNF Protein, MGC80898 Protein, BRD1 Protein, brd1 Protein, im:7138929 Protein, si:dkey-164m14.6 Protein, LOC733743 Protein, MGC146307 Protein, BRL Protein, BRPF1 Protein, BRPF2 Protein, 1110059H06Rik Protein, AI316859 Protein, mKIAA4191 Protein, bromodomain containing 1 Protein, bromodomain containing 1 L homeolog Protein, bromodomain containing 1a Protein, BRD1 Protein, brd1.L Protein, brd1a Protein, brd1 Protein, Brd1 Protein
- Background
- Bromodomain-containing protein 1 (BRD1) belongs to the BET subclass of proteins, which are characterized by two N-terminal bromodomains and one ET (Extra Terminal) domain. BRDs associate with chromatin through their bromodomains that recognize acetylated histone lysine residues. Bromodomains function as 'readers' of these epigenetic histone marks and regulate chromatin structure and gene expression by linking associated proteins to the acetylated nucleosomal targets. The ET domain functions as a protein binding motif and exerts atypical serine-kinase activity. The BET family consists of several members that function in the regulation of transcriptional activation and chromatin remodeling.
- Molecular Weight
- 21.5 kDa
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