Complement Factor B Protein (CFB) (Myc-DYKDDDDK Tag)

Catalog No. ABIN2712456

This Recombinant Complement Factor B protein is produced in HEK-293 Cells.

Quick Overview for Complement Factor B Protein (CFB) (Myc-DYKDDDDK Tag) (ABIN2712456)

Target: Complement Factor B (CFB)

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Application: Antibody Production (AbP), Standard (STD)

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Product Details

Purification tag / Conjugate: This Complement Factor B protein is labelled with Myc-DYKDDDDK Tag.

Characteristics:

• Recombinant human Complement factor B protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: Complement Factor B (CFB)

Alternative Name: Complement Factor B

Background: Factor B which is part of the alternate pathway of the complement system is cleaved by factor D into 2 fragments: Ba and Bb. Bb, a serine protease, then combines with complement factor 3b to generate the C3 or C5 convertase. It has also been implicated in proliferation and differentiation of preactivated B-lymphocytes, rapid spreading of peripheral blood monocytes, stimulation of lymphocyte blastogenesis and lysis of erythrocytes. Ba inhibits the proliferation of preactivated B-lymphocytes. [UniProtKB/Swiss-Prot Function]

Molecular Weight: 83 kDa

NCBI Accession: NP_001701

Pathways: Complement System, Proton Transport, Ribonucleoside Biosynthetic Process