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COPS5 Protein (Myc-DYKDDDDK Tag)

COPS5 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2712494
  • Target See all COPS5 Proteins
    COPS5 (COP9 Constitutive Photomorphogenic Homolog Subunit 5 (Arabidopsis) (COPS5))
    Protein Type
    Recombinant
    Origin
    • 3
    • 1
    • 1
    • 1
    • 1
    Human
    Source
    • 3
    • 2
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This COPS5 protein is labelled with Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human COPS5 protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product COPS5 Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    COPS5 (COP9 Constitutive Photomorphogenic Homolog Subunit 5 (Arabidopsis) (COPS5))
    Alternative Name
    Cops5 (COPS5 Products)
    Synonyms
    BcDNA.LD14392 Protein, BcDNA:LD14392 Protein, CG14884 Protein, CH5 Protein, CSN-5 Protein, Csn5 Protein, DCH5 Protein, Dch5 Protein, Dmel\\CG14884 Protein, JAB1 Protein, JAB1/CSN5 Protein, Jab1 Protein, JadBp Protein, csn5 Protein, dch5 Protein, jab1/csn5 Protein, l(3)89Cf Protein, l(3)L4032 Protein, l(3)M203 Protein, quo Protein, COPS5 Protein, MGC76063 Protein, AI303502 Protein, CSN5 Protein, Mov34 Protein, Sgn5 Protein, zgc:73130 Protein, MOV-34 Protein, SGN5 Protein, COP9 signalosome subunit 5 Protein, COP9 signalosome complex subunit 5 Protein, COP9 signalosome subunit 5 S homeolog Protein, CSN5 Protein, COPS5 Protein, cops5 Protein, CpipJ_CPIJ012314 Protein, Bm1_46585 Protein, VDBG_06932 Protein, LOAG_01443 Protein, csn5 Protein, Cops5 Protein, cops5.S Protein, csn-5 Protein
    Background
    The protein encoded by this gene is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. This protein is reported to be involved in the degradation of cyclin-dependent kinase inhibitor CDKN1B/p27Kip1. It is also known to be an coactivator that increases the specificity of JUN/AP1 transcription factors.
    Molecular Weight
    37.4 kDa
    NCBI Accession
    NP_006828
    Pathways
    Cell Division Cycle
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