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Coronin 7 Protein (CORO7) (Myc-DYKDDDDK Tag)

CORO7 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2712510
  • Target See all Coronin 7 (CORO7) Proteins
    Coronin 7 (CORO7)
    Protein Type
    Recombinant
    Origin
    • 1
    • 1
    • 1
    Human
    Source
    • 2
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This Coronin 7 protein is labelled with Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human Coronin-7 protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product CORO7 Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    Coronin 7 (CORO7)
    Abstract
    CORO7 Products
    Synonyms
    coronin-7 Protein, zgc:112352 Protein, MGC99303 Protein, Coronin-7 Protein, DKFZp459E084 Protein, 0610011B16Rik Protein, CRN7 Protein, POD1 Protein, AW048373 Protein, AW556392 Protein, Crn7 Protein, coronin 7 Protein, coronin 7 S homeolog Protein, coronin-7 Protein, CORO7 Protein, coro7 Protein, coro7.S Protein, LOC100477739 Protein, Coro7 Protein
    Background
    This gene encodes a member of the coronin protein family. However, unlike other coronin proteins, it is not an actin-binding protein but rather functions as an F-actin regulator directing anterograde Golgi to endosome transport. The encoded protein has two tandem WD-40 domain repeats and localizes to the trans-Golgi network. The protein undergoes K33-linked polyubiquitination via an E3 ligase complex. It is thought to play an essential role in maintenance of Golgi apparatus morphology. Alternative splicing results in multiple transcripts variants some of which form read-through transcripts with a neighboring gene.
    Molecular Weight
    100.4 kDa
    NCBI Accession
    NP_078811
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