Cortactin Protein (CTTN) (DYKDDDDK Tag)
Quick Overview for Cortactin Protein (CTTN) (DYKDDDDK Tag) (ABIN2712519)
Target
See all Cortactin (CTTN) ProteinsProtein Type
Origin
Source
Application
Purity
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Purification tag / Conjugate
- This Cortactin protein is labelled with DYKDDDDK Tag.
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Characteristics
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- Recombinant human Cortactin (full length, C-term DDK tag, transcript variant 2) protein expressed in Sf9 cells.
- Produced with end-sequenced ORF clone
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Cortactin (CTTN) (AA 1-513) protein (GST tag)
CTTN Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Cortactin (CTTN) (AA 341-450) protein (GST tag)CTTN Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Cortactin (CTTN) (Transcript Variant 2) protein (Myc-DYKDDDDK Tag)CTTN Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Comment
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 50 mM Tris-HCl, pH 8.0, 100 mM glycine, 10 % glycerol.
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Storage
- -80 °C
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Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Cortactin (CTTN)
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Alternative Name
- Cortactin
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Background
- This gene is overexpressed in breast cancer and squamous cell carcinomas of the head and neck. The encoded protein is localized in the cytoplasm and in areas of the cell-substratum contacts. This gene has two roles: (1) regulating the interactions between components of adherens-type junctions and (2) organizing the cytoskeleton and cell adhesion structures of epithelia and carcinoma cells. During apoptosis, the encoded protein is degraded in a caspase-dependent manner. The aberrant regulation of this gene contributes to tumor cell invasion and metastasis. Three splice variants that encode different isoforms have been identified for this gene.
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Molecular Weight
- 57.3 kDa
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NCBI Accession
- NP_612632
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Pathways
- MAPK Signaling
Target
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