CXCL11 Protein
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- Target See all CXCL11 Proteins
- CXCL11 (Chemokine (C-X-C Motif) Ligand 11 (CXCL11))
- Protein Type
- Recombinant
- Biological Activity
- Active
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Application
- Functional Studies (Func), Standard (STD), Antibody Production (AbP), Protein Interaction (PI)
- Specificity
- Optimal preservation of protein structure, post-translational modifications and functions.
- Characteristics
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- Recombinant human CXCL11 / ITAC protein expressed in E. coli.
- Produced with end-sequenced ORF clone
- Tested for bioactivity.
- Purity
- > 95 % as determined by SDS-PAGE and Coomassie blue staining
- Endotoxin Level
- Endotoxin level is <0.1 ng/μg of protein (<1EU/μg).
- Biological Activity Comment
- Determined by its ability to chemoattract IL-2 activated T-cells using a concentration range of 0.1-10.0 ng/ml.
- Top Product
- Discover our top product CXCL11 Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays
Protein-protein interaction
In vitro biochemical assays and cell-based functional assays - Restrictions
- For Research Use only
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- Buffer
- Lyophilized from a 0.2 μM filtered solution of 20 mM phosphate buffer,100 mM NaCl, pH 7.2
- Handling Advice
- Resuspend the protein in the desired concentration in proper buffer
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- CXCL11 (Chemokine (C-X-C Motif) Ligand 11 (CXCL11))
- Alternative Name
- Cxcl11,itac (CXCL11 Products)
- Synonyms
- H174 Protein, I-TAC Protein, IP-9 Protein, IP9 Protein, SCYB11 Protein, SCYB9B Protein, b-R1 Protein, Cxc11 Protein, I-tac Protein, Ip9 Protein, Itac Protein, Scyb11 Protein, Scyb9b Protein, betaR1 Protein, C-X-C motif chemokine ligand 11 Protein, chemokine (C-X-C motif) ligand 11 Protein, CXCL11 Protein, Cxcl11 Protein
- Background
- Chemotactic for interleukin-activated T-cells but not unstimulated T-cells, neutrophils or monocytes. Induces calcium release in activated T-cells. Binds to CXCR3. May play an important role in CNS diseases which involve T-cell recruitment. May play a role in skin immune responses. [UniProtKB/Swiss-Prot Function]
- Molecular Weight
- 8.3 kDa
- NCBI Accession
- NP_005400
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