Caveolin 2 Protein (CAV2) (His tag)

Catalog No. ABIN2713246

Product Details

Target: Caveolin 2 (CAV2)

Protein Type: Recombinant

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This Caveolin 2 protein is labelled with His tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human Caveolin-2 (full length, N-term HIS tag, transcript variant 2) protein expressed in E. coli.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the N-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris, pH 8.0, 150 mM NaCl, 10 % glycerol, 1 % Sarkosyl. Store at -80C. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: Caveolin 2 (CAV2)

Alternative Name: Caveolin-2 (CAV2 Products)

Synonyms: CAV Protein, AI447843 Protein, cav-2 Protein, zgc:86696 Protein, wu:fc52e01 Protein, caveolin-2 Protein, CAV-2 Protein, Caveolin-2 Protein, Cav-2 Protein, cav Protein, cav2 Protein, caveolin 2 Protein, caveolin 2 L homeolog Protein, caveolin-2 Protein, Caveolin-2 Protein, CAV2 Protein, Cav2 Protein, cav2.L Protein, cav2 Protein, LOC100093133 Protein, cav-2 Protein

Background: The protein encoded by this gene is a major component of the inner surface of caveolae, small invaginations of the plasma membrane, and is involved in essential cellular functions, including signal transduction, lipid metabolism, cellular growth control and apoptosis. This protein may function as a tumor suppressor. This gene and related family member (CAV1) are located next to each other on chromosome 7, and express colocalizing proteins that form a stable hetero-oligomeric complex. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. Additional isoforms resulting from the use of alternate in-frame translation initiation codons have also been described, and shown to have preferential localization in the cell (PMID:11238462).

Molecular Weight: 12.6 kDa

NCBI Accession: NP_937855

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling, Skeletal Muscle Fiber Development