CBFA2T3 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)
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- Target See all CBFA2T3 Proteins
- CBFA2T3 (Core-binding Factor, Runt Domain, alpha Subunit 2, Translocated To, 3 (CBFA2T3))
- Protein Type
- Recombinant
- Protein Characteristics
- Transcript Variant 1
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This CBFA2T3 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human CBFA2T3 (transcript variant 1) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product CBFA2T3 Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- CBFA2T3 (Core-binding Factor, Runt Domain, alpha Subunit 2, Translocated To, 3 (CBFA2T3))
- Alternative Name
- Cbfa2t3 (CBFA2T3 Products)
- Synonyms
- A630044F12Rik Protein, AI465270 Protein, AW229127 Protein, Cbfa2t3h Protein, ETO-2 Protein, Eto2 Protein, MTGR2 Protein, MTG16a Protein, MTG16b Protein, ETO2 Protein, MTG16 Protein, ZMYND4 Protein, core-binding factor, runt domain, alpha subunit 2, translocated to, 3 (human) Protein, CBFA2/RUNX1 translocation partner 3 Protein, Cbfa2t3 Protein, CBFA2T3 Protein
- Background
- This gene encodes a member of the myeloid translocation gene family which interact with DNA-bound transcription factors and recruit a range of corepressors to facilitate transcriptional repression. The t(1621)(q24q22) translocation is one of the less common karyotypic abnormalities in acute myeloid leukemia. The translocation produces a chimeric gene made up of the 5&apos-region of the runt-related transcription factor 1 gene fused to the 3&apos-region of this gene. This gene is also a putative breast tumor suppressor. Alternative splicing results in transcript variants.
- Molecular Weight
- 71 kDa
- NCBI Accession
- NP_005178
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