HSD17B8 Protein (Myc-DYKDDDDK Tag)

Catalog No. ABIN2714226

Product Details

Target: HSD17B8 (Hydroxysteroid (17-Beta) Dehydrogenase 8 (HSD17B8))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This HSD17B8 protein is labelled with Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human 17-beta HSD8 / HSD17B8 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: HSD17B8 (Hydroxysteroid (17-Beta) Dehydrogenase 8 (HSD17B8))

Alternative Name: 17-beta Hsd8,hsd17b8 (HSD17B8 Products)

Synonyms: KE6 Protein, fabgl Protein, zgc:112550 Protein, si:dz12f11.4 Protein, HKE6 Protein, FABGL Protein, ke6 Protein, fabg Protein, hke6 Protein, ring2 Protein, h2-ke6 Protein, d6s2245e Protein, D17H6S112E Protein, H-2Ke6 Protein, Hsd17b8 Protein, Ke-6 Protein, Ke6 Protein, Ring2 Protein, D6S2245E Protein, FABG Protein, H2-KE6 Protein, RING2 Protein, SDR30C1 Protein, dJ1033B10.9 Protein, Fabgl Protein, hydroxysteroid (17-beta) dehydrogenase 8 Protein, hydroxysteroid 17-beta dehydrogenase 8 Protein, H2-K region expressed gene 6 Protein, hsd17b8 Protein, HSD17B8 Protein, H2-Ke6 Protein, Hsd17b8 Protein

Background: In mice, the Ke6 protein is a 17-beta-hydroxysteroid dehydrogenase that can regulate the concentration of biologically active estrogens and androgens. It is preferentially an oxidative enzyme and inactivates estradiol, testosterone, and dihydrotestosterone. However, the enzyme has some reductive activity and can synthesize estradiol from estrone. The protein encoded by this gene is similar to Ke6 and is a member of the short-chain dehydrogenase superfamily. An alternatively spliced transcript of this gene has been detected, but the full-length nature of this variant has not been determined.

Molecular Weight: 26.8 kDa

NCBI Accession: NP_055049

Pathways: Steroid Hormone Biosynthesis