Beclin 1 Protein (Myc-DYKDDDDK Tag)
(1 reference)-
- Target See all Beclin 1 (BECN1) Proteins
- Beclin 1 (BECN1) (Beclin 1, Autophagy Related (BECN1))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This Beclin 1 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human Beclin-1 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product BECN1 Protein
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Beclin 1, Autophagy Related (BECN1) (AA 1-450) protein (GST tag)
BECN1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Beclin 1, Autophagy Related (BECN1) (AA 46-152) protein (His-IF2DI Tag)BECN1 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Beclin 1, Autophagy Related (BECN1) (AA 351-450) protein (GST tag)BECN1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Beclin 1, Autophagy Related (BECN1) (AA 1-450) protein (His tag)BECN1 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Beclin 1, Autophagy Related (BECN1) (AA 1-450) protein (Strep Tag)Crystallography grade BECN1 Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
Beclin 1, Autophagy Related (BECN1) (AA 1-448) protein (Strep Tag)Crystallography grade BECN1 Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
Beclin 1, Autophagy Related (BECN1) (AA 150-450) protein (His tag)Crystallography grade BECN1 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Beclin 1, Autophagy Related (BECN1) (AA 134-450) protein (His tag)Crystallography grade BECN1 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Beclin 1, Autophagy Related (BECN1) (AA 132-448) protein (His tag)Crystallography grade BECN1 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Beclin 1, Autophagy Related (BECN1) (AA 148-448) protein (His tag)Crystallography grade BECN1 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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: "Cytosolic HMGB1 controls the cellular autophagy/apoptosis checkpoint during inflammation." in: The Journal of clinical investigation, Vol. 125, Issue 3, pp. 1098-110, (2015) (PubMed).
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: "Cytosolic HMGB1 controls the cellular autophagy/apoptosis checkpoint during inflammation." in: The Journal of clinical investigation, Vol. 125, Issue 3, pp. 1098-110, (2015) (PubMed).
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- Target
- Beclin 1 (BECN1) (Beclin 1, Autophagy Related (BECN1))
- Alternative Name
- Beclin-1 (BECN1 Products)
- Synonyms
- beclin-1 Protein, atg6 Protein, vps30 Protein, beclin1 Protein, Beclin-1 Protein, becn1 Protein, zgc:73097 Protein, ATG6 Protein, VPS30 Protein, 4921513J16Rik Protein, 5430417M23Rik Protein, Atg6 Protein, beclin 1 Protein, beclin 1, autophagy related Protein, beclin 1 protein Protein, beclin-1 Protein, beclin family protein Protein, beclin 1, autophagy related L homeolog Protein, BECN1 Protein, becn1 Protein, atg6 Protein, CpipJ_CPIJ011087 Protein, PTRG_07825 Protein, SJAG_01876 Protein, Becn1 Protein, becn1.L Protein
- Background
- This gene encodes a protein that regulates autophagy, a catabolic process of degradation induced by starvation. The encoded protein is a component of the phosphatidylinositol-3-kinase (PI3K) complex which mediates vesicle-trafficking processes. This protein is thought to play a role in multiple cellular processes, including tumorigenesis, neurodegeneration and apoptosis. Alternative splicing results in multiple transcript variants.
- Molecular Weight
- 51.7 kDa
- NCBI Accession
- NP_003757
- Pathways
- Autophagy
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