BIK Protein (His tag)
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- Target See all BIK Proteins
- BIK (BCL2-Interacting Killer (Apoptosis-Inducing) (BIK))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This BIK protein is labelled with His tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human BIK (full length, N-term HIS tag) protein expressed in E. coli.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product BIK Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the N-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris, pH 8.0, 150 mM NaCl, 10 % glycerol, 1 % Sarkosyl.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- BIK (BCL2-Interacting Killer (Apoptosis-Inducing) (BIK))
- Alternative Name
- Bik (BIK Products)
- Synonyms
- BIK Protein, Biklk Protein, Blk Protein, Nbk Protein, BIP1 Protein, BP4 Protein, NBK Protein, si:dkey-31f5.6 Protein, BCL2 interacting killer Protein, BCL2-interacting killer Protein, BCL2-interacting killer (apoptosis-inducing) Protein, BIK Protein, Bik Protein, bik Protein
- Background
- The protein encoded by this gene shares a critical BH3 domain with other death-promoting proteins, such as BID, BAK, BAD and BAX, that is required for its pro-apoptotic activity, and for interaction with anti-apoptotic members of the BCL2 family, and viral survival-promoting proteins. Since the activity of this protein is suppressed in the presence of survival-promoting proteins, it is suggested as a likely target for anti-apoptotic proteins.
- Molecular Weight
- 17.8 kDa
- NCBI Accession
- NP_001188
- Pathways
- Positive Regulation of Endopeptidase Activity
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