CAMK2A Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)
-
- Target See all CAMK2A Proteins
- CAMK2A (Calcium/calmodulin-Dependent Protein Kinase II alpha (CAMK2A))
- Protein Type
- Recombinant
- Protein Characteristics
- Transcript Variant 1
-
Origin
- Human
-
Source
- HEK-293 Cells
- Purification tag / Conjugate
- This CAMK2A protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
-
- Recombinant human Calcium/calmodulin-dependent protein kinase II alpha (CAMK2A), transcript variant 1 (transcript variant 1) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product CAMK2A Protein
-
-
- Application Notes
-
Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
-
The tag is located at the C-terminal.
- Restrictions
- For Research Use only
-
- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
-
- Target
- CAMK2A (Calcium/calmodulin-Dependent Protein Kinase II alpha (CAMK2A))
- Abstract
- CAMK2A Products
- Synonyms
- camk2 Protein, camk2b Protein, zgc:112538 Protein, zgc:123320 Protein, CAMKA Protein, CaMKII Protein, R74975 Protein, mKIAA0968 Protein, PK2CDD Protein, PKCCD Protein, calcium/calmodulin dependent protein kinase II alpha Protein, calcium/calmodulin dependent protein kinase (CaM kinase) II alpha S homeolog Protein, calcium/calmodulin-dependent protein kinase II alpha Protein, CAMK2A Protein, camk2a.S Protein, camk2a Protein, Camk2a Protein
- Background
- The product of this gene belongs to the serine/threonine protein kinases family, and to the Ca(2+)/calmodulin-dependent protein kinases subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. This calcium calmodulin-dependent protein kinase is composed of four different chains: alpha, beta, gamma, and delta. The alpha chain encoded by this gene is required for hippocampal long-term potentiation (LTP) and spatial learning. In addition to its calcium-calmodulin (CaM)-dependent activity, this protein can undergo autophosphorylation, resulting in CaM-independent activity. Two transcript variants encoding distinct isoforms have been identified for this gene.
- Molecular Weight
- 55.1 kDa
- NCBI Accession
- NP_057065
- Pathways
- WNT Signaling, Interferon-gamma Pathway, Myometrial Relaxation and Contraction
-