beta Defensin 1 Protein
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- Target See all beta Defensin 1 (DEFB1) Proteins
- beta Defensin 1 (DEFB1) (Defensin, beta 1 (DEFB1))
- Protein Type
- Recombinant
- Biological Activity
- Active
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Application
- Functional Studies (Func), Antibody Production (AbP), Standard (STD), Protein Interaction (PI)
- Specificity
- Optimal preservation of protein structure, post-translational modifications and functions.
- Characteristics
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- Recombinant human Defensin beta 1 protein expressed in E. coli.
- Produced with end-sequenced ORF clone
- Tested for bioactivity.
- Purity
- > 95 % as determined by SDS-PAGE and Coomassie blue staining
- Endotoxin Level
- Endotoxin level is <0.1 ng/μg of protein (<1EU/μg).
- Biological Activity Comment
- Determined by its ability to chemoattract CD34+ dendritic cells using a concentration range of 100.0-1000.0 ng/ml.
- Top Product
- Discover our top product DEFB1 Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays
Protein-protein interaction
In vitro biochemical assays and cell-based functional assays - Restrictions
- For Research Use only
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- Buffer
- Lyophilized from a 0.2 μM filtered solution of 20 mM phosphate buffer,100 mM NaCl, pH 7.2
- Handling Advice
- Resuspend the protein in the desired concentration in proper buffer
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- beta Defensin 1 (DEFB1) (Defensin, beta 1 (DEFB1))
- Alternative Name
- Defensin beta 1 (DEFB1 Products)
- Synonyms
- BD1 Protein, DEFB-1 Protein, DEFB101 Protein, HBD1 Protein, AW260221 Protein, BD-1 Protein, DEFB1-like Protein, RHBD-1 Protein, CBD1 Protein, PBD-1 Protein, DEFB1 Protein, BNBD-1 Protein, defensin beta 1 Protein, avian beta-defensin 1 Protein, defensin, beta 1 Protein, beta-defensin 1-like Protein, beta-defensin 1 Protein, DEFB1 Protein, Defb1 Protein, AvBD1 Protein, LOC100861170 Protein
- Background
- Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. Members of the defensin family are highly similar in protein sequence. This gene encodes defensin, beta 1, an antimicrobial peptide implicated in the resistance of epithelial surfaces to microbial colonization. This gene maps in close proximity to defensin family member, defensin, alpha 1 and has been implicated in the pathogenesis of cystic fibrosis.
- Molecular Weight
- 5 kDa
- NCBI Accession
- NP_005209
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