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Deoxyguanosine Kinase Protein (DGUOK) (Transcript Variant 1) (Myc-DYKDDDDK Tag)

DGUOK Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2719393
  • Target See all Deoxyguanosine Kinase (DGUOK) Proteins
    Deoxyguanosine Kinase (DGUOK)
    Protein Type
    Recombinant
    Protein Characteristics
    Transcript Variant 1
    Origin
    • 4
    • 1
    Human
    Source
    • 3
    • 2
    HEK-293 Cells
    Purification tag / Conjugate
    This Deoxyguanosine Kinase protein is labelled with Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human Deoxyguanosine kinase (transcript variant 1) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product DGUOK Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    Deoxyguanosine Kinase (DGUOK)
    Alternative Name
    Deoxyguanosine Kinase (DGUOK Products)
    Synonyms
    DGUOK Protein, zgc:86625 Protein, dgk Protein, DDBDRAFT_0218264 Protein, DDBDRAFT_0233982 Protein, DDB_0218264 Protein, DDB_0233982 Protein, MTDPS3 Protein, dGK Protein, dGK1 Protein, dGK2 Protein, dGK3 Protein, deoxyguanosine kinase Protein, deoxyguanosine kinase L homeolog Protein, DGUOK Protein, dguok Protein, dguok.L Protein, dgk Protein, Ccan_04750 Protein, Dguok Protein
    Background
    In mammalian cells, the phosphorylation of purine deoxyribonucleosides is mediated predominantly by two deoxyribonucleoside kinases, cytosolic deoxycytidine kinase and mitochondrial deoxyguanosine kinase. The protein encoded by this gene is responsible for phosphorylation of purine deoxyribonucleosides in the mitochondrial matrix. In addition, this protein phosphorylates several purine deoxyribonucleoside analogs used in the treatment of lymphoproliferative disorders, and this phosphorylation is critical for the effectiveness of the analogs. Alternative splice variants encoding different protein isoforms have been described for this gene.
    Molecular Weight
    27.9 kDa
    NCBI Accession
    NP_550438
    Pathways
    Ribonucleoside Biosynthetic Process
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