DGCR8 Protein (Myc-DYKDDDDK Tag)

Catalog No. ABIN2719439

Product Details

Target: DGCR8 (DiGeorge Syndrome Critical Region Gene 8 (DGCR8))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This DGCR8 protein is labelled with Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human DGCR8 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: DGCR8 (DiGeorge Syndrome Critical Region Gene 8 (DGCR8))

Alternative Name: Dgcr8 (DGCR8 Products)

Synonyms: MGC78846 Protein, DGCR8 Protein, gy1 Protein, dgcrk6 Protein, C22orf12 Protein, DGCRK6 Protein, Gy1 Protein, pasha Protein, D16H22S1742E Protein, D16H22S788E Protein, D16Wis2 Protein, N41 Protein, Vo59c07 Protein, si:ch211-106a19.4 Protein, wu:fc23f08 Protein, wu:fc38f06 Protein, DGCR8 microprocessor complex subunit L homeolog Protein, DiGeorge syndrome critical region gene 8 Protein, DGCR8 microprocessor complex subunit Protein, DGCR8, microprocessor complex subunit Protein, microRNA 3618 Protein, dgcr8.L Protein, DGCR8 Protein, dgcr8 Protein, Dgcr8 Protein, MIR3618 Protein

Background: This gene encodes a subunit of the microprocessor complex which mediates the biogenesis of microRNAs from the primary microRNA transcript. The encoded protein is a double-stranded RNA binding protein that functions as the non-catalytic subunit of the microprocessor complex. This protein is required for binding the double-stranded RNA substrate and facilitates cleavage of the RNA by the ribonuclease III protein, Drosha. Alternate splicing results in multiple transcript variants.

Molecular Weight: 85.9 kDa

NCBI Accession: NP_073557

Pathways: Regulatory RNA Pathways