DOK7 Protein (Myc-DYKDDDDK Tag)
-
- Target See all DOK7 Proteins
- DOK7 (Docking Protein 7 (DOK7))
- Protein Type
- Recombinant
-
Origin
- Human
-
Source
- HEK-293 Cells
- Purification tag / Conjugate
- This DOK7 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
-
- Recombinant human DOK7 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product DOK7 Protein
-
-
- Application Notes
-
Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
-
The tag is located at the C-terminal.
- Restrictions
- For Research Use only
-
- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
-
- Target
- DOK7 (Docking Protein 7 (DOK7))
- Alternative Name
- Dok7 (DOK7 Products)
- Synonyms
- si:dkey-180b4.3 Protein, si:ch211-164d19.2 Protein, C4orf25 Protein, CMS1B Protein, A930013K19Rik Protein, AW049091 Protein, Dok-7 Protein, EF-12 Protein, Oit5 Protein, RGD1566416 Protein, dok-7 Protein, docking protein 7 Protein, DOK7 Protein, dok7 Protein, Dok7 Protein
- Background
- The protein encoded by this gene is essential for neuromuscular synaptogenesis. The protein functions in aneural activation of muscle-specific receptor kinase, which is required for postsynaptic differentiation, and in the subsequent clustering of the acetylcholine receptor in myotubes. This protein can also induce autophosphorylation of muscle-specific receptor kinase. Mutations in this gene are a cause of familial limb-girdle myasthenia autosomal recessive, which is also known as congenital myasthenic syndrome type 1B. Alternative splicing results in multiple transcript variants.
- Molecular Weight
- 52.9 kDa
- NCBI Accession
- NP_775931
- Pathways
- Skeletal Muscle Fiber Development
-