DUSP11 Protein (His tag)
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- Target See all DUSP11 Proteins
- DUSP11 (Dual Specificity Phosphatase 11 (RNA/RNP Complex 1-Interacting) (DUSP11))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This DUSP11 protein is labelled with His tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human DUSP11 (full length, N-term HIS tag) protein expressed in E. coli.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product DUSP11 Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the N-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 50 mM Tris, 8M Urea, pH 8.0.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- DUSP11 (Dual Specificity Phosphatase 11 (RNA/RNP Complex 1-Interacting) (DUSP11))
- Alternative Name
- Dusp11 (DUSP11 Products)
- Synonyms
- pir1 Protein, DUSP11 Protein, 2010300F21Rik Protein, AI481497 Protein, wu:fa05e01 Protein, wu:fc09a06 Protein, wu:fk47e10 Protein, zgc:112166 Protein, PIR1 Protein, dusp11 Protein, dual specificity phosphatase 11 Protein, dual specificity phosphatase 11 (RNA/RNP complex 1-interacting) Protein, dual specificity phosphatase 11 L homeolog Protein, DUSP11 Protein, DUSP11RC1I Protein, dusp11 Protein, Dusp11 Protein, dusp11.L Protein
- Background
- The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product is localized to the nucleus and binds directly to RNA and splicing factors, and thus it is suggested to participate in nuclear mRNA metabolism.
- Molecular Weight
- 38.8 kDa
- NCBI Accession
- NP_003575
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