EDAR Protein (Myc-DYKDDDDK Tag)
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- Target See all EDAR Proteins
- EDAR (Ectodysplasin A Receptor (EDAR))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This EDAR protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human EDAR protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product EDAR Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- EDAR (Ectodysplasin A Receptor (EDAR))
- Alternative Name
- Edar (EDAR Products)
- Synonyms
- rs3 Protein, edar Protein, EDAR Protein, MGC88893 Protein, DL Protein, ECTD10A Protein, ECTD10B Protein, ED1R Protein, ED3 Protein, ED5 Protein, EDA-A1R Protein, EDA1R Protein, EDA3 Protein, HRM1 Protein, dl Protein, RGD1561714 Protein, ectodysplasin A receptor Protein, ectodysplasin-A receptor Protein, edar Protein, EDAR Protein, Edar Protein
- Background
- This gene encodes a member of the tumor necrosis factor receptor family. The encoded transmembrane protein is a receptor for the soluble ligand ectodysplasin A, and can activate the nuclear factor-kappaB, JNK, and caspase-independent cell death pathways. It is required for the development of hair, teeth, and other ectodermal derivatives. Mutations in this gene result in autosomal dominant and recessive forms of hypohidrotic ectodermal dysplasia.
- Molecular Weight
- 45.8 kDa
- NCBI Accession
- NP_071731
- Pathways
- Tube Formation, Ubiquitin Proteasome Pathway
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