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FGD1 Protein (Myc-DYKDDDDK Tag)

FGD1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2721027
  • Target See all FGD1 Proteins
    FGD1 (FYVE, RhoGEF and PH Domain Containing 1 (FGD1))
    Protein Type
    Recombinant
    Origin
    • 1
    • 1
    Human
    Source
    • 2
    HEK-293 Cells
    Purification tag / Conjugate
    This FGD1 protein is labelled with Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human FGD1 protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product FGD1 Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    FGD1 (FYVE, RhoGEF and PH Domain Containing 1 (FGD1))
    Alternative Name
    Fgd1 (FGD1 Products)
    Synonyms
    AAS Protein, FGDY Protein, MRXS16 Protein, ZFYVE3 Protein, FYVE, RhoGEF and PH domain containing 1 Protein, FGD1 Protein, Fgd1 Protein, fgd1 Protein
    Background
    This gene encodes a protein that contains Dbl (DH) and pleckstrin (PH) homology domains and is similar to the Rho family of small GTP-binding proteins. The encoded protein specifically binds to the Rho family GTPase Cdc42Hs and can stimulate the GDP-GTP exchange of the isoprenylated form of Cdc42Hs. It also stimulates the mitogen activated protein kinase cascade leading to c-Jun kinase SAPK/JNK1 activation. Defects in this gene are the cause of faciogenital dysplasia and X-linked mental retardation, syndromatic 16.[provided by RefSeq, Mar 2011]
    Molecular Weight
    106.4 kDa
    NCBI Accession
    NP_004454
    Pathways
    Neurotrophin Signaling Pathway
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