FGD1 Protein (Myc-DYKDDDDK Tag)
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- Target See all FGD1 Proteins
- FGD1 (FYVE, RhoGEF and PH Domain Containing 1 (FGD1))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This FGD1 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human FGD1 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product FGD1 Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- FGD1 (FYVE, RhoGEF and PH Domain Containing 1 (FGD1))
- Alternative Name
- Fgd1 (FGD1 Products)
- Synonyms
- AAS Protein, FGDY Protein, MRXS16 Protein, ZFYVE3 Protein, FYVE, RhoGEF and PH domain containing 1 Protein, FGD1 Protein, Fgd1 Protein, fgd1 Protein
- Background
- This gene encodes a protein that contains Dbl (DH) and pleckstrin (PH) homology domains and is similar to the Rho family of small GTP-binding proteins. The encoded protein specifically binds to the Rho family GTPase Cdc42Hs and can stimulate the GDP-GTP exchange of the isoprenylated form of Cdc42Hs. It also stimulates the mitogen activated protein kinase cascade leading to c-Jun kinase SAPK/JNK1 activation. Defects in this gene are the cause of faciogenital dysplasia and X-linked mental retardation, syndromatic 16.[provided by RefSeq, Mar 2011]
- Molecular Weight
- 106.4 kDa
- NCBI Accession
- NP_004454
- Pathways
- Neurotrophin Signaling Pathway
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