FREM1 Protein (Myc-DYKDDDDK Tag)
FREM1
Origin: Human
Host: HEK-293 Cells
Recombinant
> 80 % as determined by SDS-PAGE and Coomassie blue staining
AbP, STD
1 image
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- Target See all FREM1 products
- FREM1 (FRAS1 Related Extracellular Matrix 1 (FREM1))
- Protein Type
- Recombinant
- Origin
- Human
- Source
- HEK-293 Cells
- Purification tag / Conjugate
- This FREM1 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human FREM1 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- FREM1 (FRAS1 Related Extracellular Matrix 1 (FREM1))
- Alternative Name
- Frem1 (FREM1 Products)
- Synonyms
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BNAR Protein, C9orf143 Protein, C9orf145 Protein, C9orf154 Protein, MOTA Protein, TILRR Protein, TRIGNO2 Protein, RGD1306981 Protein, BC037594 Protein, D430009N09 Protein, D630008K06 Protein, eye
Protein, eyes2 Protein, heb Protein, qbrick Protein, FRAS1 related extracellular matrix 1 Protein, Fras1 related extracellular matrix 1 Protein, Fras1 related extracellular matrix protein 1 Protein, FREM1 Protein, Frem1 Protein - Background
- This gene encodes a basement membrane protein that may play a role in craniofacial and renal development. Mutations in this gene have been associated with bifid nose with or without anorectal and renal anomalies. Alternatively spliced transcript variants encoding different isoforms have been described. PubMed ID 19940113 describes one such variant that initiates transcription within a distinct, internal exon the resulting shorter isoform (named Toll-like/interleukin-1 receptor regulator, TILRR) is suggested to be a co-receptor of the interleukin 1 receptor family and may regulate receptor function and Toll-like receptor/interleukin 1 receptor signal transduction, contributing to the control of inflammatory response activation.
- Molecular Weight
- 241.9 kDa
- NCBI Accession
- NP_659403
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