GLE1 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)
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- Target See all GLE1 Proteins
- GLE1 (GLE1 RNA Export Mediator (GLE1))
- Protein Type
- Recombinant
- Protein Characteristics
- Transcript Variant 1
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This GLE1 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human GLE1 / GLE1L (transcript variant 1) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product GLE1 Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- GLE1 (GLE1 RNA Export Mediator (GLE1))
- Alternative Name
- Gle1,gle1l (GLE1 Products)
- Synonyms
- Dmel\\CG14749 Protein, GLE1 Protein, GLE1L Protein, LCCS Protein, LCCS1 Protein, hGLE1 Protein, Gle1l Protein, 4933405K21Rik Protein, AA553313 Protein, CG14749 gene product from transcript CG14749-RA Protein, nucleoporin GLE1 Protein, RNA export factor Gle1 Protein, GLE1, RNA export mediator Protein, GLE1 RNA export mediator Protein, GLE1 RNA export mediator (yeast) Protein, CG14749 Protein, CpipJ_CPIJ014147 Protein, SJAG_03847 Protein, GLE1 Protein, Gle1 Protein
- Background
- This gene encodes a predicted 75- kDa polypeptide with high sequence and structure homology to yeast Gle1p, which is nuclear protein with a leucine-rich nuclear export sequence essential for poly(A)+RNA export. Inhibition of human GLE1L by microinjection of antibodies against GLE1L in HeLa cells resulted in inhibition of poly(A)+RNA export. Immunoflourescence studies show that GLE1L is localized at the nuclear pore complexes. This localization suggests that GLE1L may act at a terminal step in the export of mature RNA messages to the cytoplasm. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene.
- Molecular Weight
- 79.7 kDa
- NCBI Accession
- NP_001003722
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