H2AFY Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)
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- Target See all H2AFY Proteins
- H2AFY (H2A Histone Family, Member Y (H2AFY))
- Protein Type
- Recombinant
- Protein Characteristics
- Transcript Variant 2
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This H2AFY protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human H2AFY / MACROH2A1 (transcript variant 2) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product H2AFY Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- H2AFY (H2A Histone Family, Member Y (H2AFY))
- Alternative Name
- h2afy,macroh2a1 (H2AFY Products)
- Synonyms
- H2A.y Protein, H2A/y Protein, H2AF12M Protein, H2AFJ Protein, MACROH2A1.1 Protein, mH2A1 Protein, macroH2A1.2 Protein, mH2a1 Protein, macroH2A1 Protein, wu:fa93c12 Protein, zgc:136891 Protein, h2a.y Protein, h2a/y Protein, h2af12m Protein, h2afj Protein, macroh2a Protein, mh2a1 Protein, core histone macro-H2A.1 Protein, H2A histone family, member Y Protein, H2A histone family member Y Protein, H2A histone family member Y L homeolog Protein, LOC100230612 Protein, H2AFY Protein, LOC481514 Protein, H2afy Protein, h2afy Protein, h2afy.L Protein
- Background
- Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a replication-independent histone that is a member of the histone H2A family. It replaces conventional H2A histones in a subset of nucleosomes where it represses transcription and participates in stable X chromosome inactivation. Alternative splicing results in multiple transcript variants encoding different isoforms.
- Molecular Weight
- 39.3 kDa
- NCBI Accession
- NP_004884
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