HIST2H2AB Protein (Myc-DYKDDDDK Tag)

Catalog No. ABIN2722792

Product Details

Target: HIST2H2AB (Hist2h2ab) (Histone Cluster 2, H2ab (Hist2h2ab))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This HIST2H2AB protein is labelled with Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human Histone cluster 2, H2ab (HIST2H2AB) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: HIST2H2AB (Hist2h2ab) (Histone Cluster 2, H2ab (Hist2h2ab))

Abstract: Hist2h2ab Products

Synonyms: h2a Protein, H2AB Protein, EG621893 Protein, H2a-613a Protein, histone cluster 2, H2ab Protein, histone cluster 2 H2A family member b Protein, zgc:163047 Protein, hist2h2ab Protein, HIST2H2AB Protein, Hist2h2ab Protein, zgc:163047 Protein

Background: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. [UniProtKB/Swiss-Prot Function]

Molecular Weight: 13.8 kDa

NCBI Accession: NP_778235