H2AFZ Protein (Myc-DYKDDDDK Tag)
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- Target See all H2AFZ Proteins
- H2AFZ (H2A Histone Family, Member Z (H2AFZ))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This H2AFZ protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human Histone H2A.Z protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product H2AFZ Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- H2AFZ (H2A Histone Family, Member Z (H2AFZ))
- Alternative Name
- Histone h2a.z (H2AFZ Products)
- Synonyms
- H2A.Z-1 Protein, H2A.z Protein, H2A/z Protein, H2AZ Protein, H2A.Z Protein, H2a.z-1 Protein, H2AFV Protein, H2Az Protein, XH2AZ Protein, h2a.zl1 Protein, h2a.zl2 Protein, H2A histone family member Z Protein, H2A histone family, member Z Protein, H2A histone family member Z L homeolog Protein, histone H2A.Z Protein, H2AFZ Protein, H2afz Protein, h2afz.L Protein
- Background
- Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a replication-independent member of the histone H2A family that is distinct from other members of the family. Studies in mice have shown that this particular histone is required for embryonic development and indicate that lack of functional histone H2A leads to embryonic lethality.
- Molecular Weight
- 13.4 kDa
- NCBI Accession
- NP_002097
- Pathways
- Telomere Maintenance
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