H2AFZ Protein (AA 1-128) (His tag)
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- Target See all H2AFZ Proteins
- H2AFZ (H2A Histone Family, Member Z (H2AFZ))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-128
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This H2AFZ protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- MGSSHHHHHH SSGLVPRGSH MGSMAGGKAG KDSGKAKTKA VSRSQRAGLQ FPVGRIHRHL KSRTTSHGRV GATAAVYSAA ILEYLTAEVL ELAGNASKDL KVKRITPRHL QLAIRGDEEL DSLIKATIAG GGVIPHIHKS LIGKKGQQKT V
- Purity
- > 85 % by SDS - PAGE
- Top Product
- Discover our top product H2AFZ Protein
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Comment
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Denatured
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.25 mg/mL
- Buffer
- Liquid. In 20 mM Tris-HCl buffer ( pH 8.0) containing 0.4M urea, 10 % glycerol
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- Target
- H2AFZ (H2A Histone Family, Member Z (H2AFZ))
- Alternative Name
- H2AFZ (H2AFZ Products)
- Synonyms
- H2A.Z-1 Protein, H2A.z Protein, H2A/z Protein, H2AZ Protein, H2A.Z Protein, H2a.z-1 Protein, H2AFV Protein, H2Az Protein, XH2AZ Protein, h2a.zl1 Protein, h2a.zl2 Protein, H2A histone family member Z Protein, H2A histone family, member Z Protein, H2A histone family member Z L homeolog Protein, histone H2A.Z Protein, H2AFZ Protein, H2afz Protein, h2afz.L Protein
- Background
- Histone H2A.Z, also known as H2AFZ, is a member of the histone H2A family. Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). H2AFZ may be involved in the formation of constitutive heterochromatin and may be required for chromosome segregation during cell division. Also, H2AFZ is a variant Histone H2A which replaces conventional H2A in a subset of nucleosomes. Recombinant human H2AFZ protein, fused to His-tag at N-terminus, was expressed in E.coli.
- Molecular Weight
- 15.9 kDa (151aa)
- NCBI Accession
- NP_002097
- UniProt
- P0C0S5
- Pathways
- Telomere Maintenance
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