BIRC3 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)
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- Target See all BIRC3 Proteins
- BIRC3 (Baculoviral IAP Repeat Containing 3 (BIRC3))
- Protein Type
- Recombinant
- Protein Characteristics
- Transcript Variant 1
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This BIRC3 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human IAP1 / BIRC3 (transcript variant 1) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product BIRC3 Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- BIRC3 (Baculoviral IAP Repeat Containing 3 (BIRC3))
- Alternative Name
- Iap1,birc3 (BIRC3 Products)
- Synonyms
- AIP1 Protein, API2 Protein, CIAP2 Protein, HAIP1 Protein, HIAP1 Protein, MALT2 Protein, MIHC Protein, RNF49 Protein, c-IAP2 Protein, Api1 Protein, Api2 Protein, IAP1 Protein, IAP2 Protein, MIHB Protein, Birc2 Protein, HIAP2 Protein, MIAP1 Protein, MIAP2 Protein, cIAP1 Protein, cIAP2 Protein, cIAP-1 Protein, cIAP-2 Protein, AW107670 Protein, BIRC2 Protein, baculoviral IAP repeat containing 3 Protein, baculoviral IAP repeat-containing 3 Protein, baculoviral IAP repeat-containing protein 3 Protein, inhibitor of apoptosis protein-2 Protein, BIRC3 Protein, Birc3 Protein, LOC100399118 Protein, OpmnVgp074 Protein
- Background
- This gene encodes a member of the IAP family of proteins that inhibit apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE-like proteases. The encoded protein inhibits apoptosis induced by serum deprivation but does not affect apoptosis resulting from exposure to menadione, a potent inducer of free radicals. It contains 3 baculovirus IAP repeats and a ring finger domain. Transcript variants encoding the same isoform have been identified.
- Molecular Weight
- 68.2 kDa
- NCBI Accession
- NP_001156
- Pathways
- Apoptosis, Caspase Cascade in Apoptosis, Activation of Innate immune Response, Toll-Like Receptors Cascades
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