IKKi/IKKe Protein (Myc-DYKDDDDK Tag)
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- Target See all IKKi/IKKe (IKBKE) Proteins
- IKKi/IKKe (IKBKE) (Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase epsilon (IKBKE))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This IKKi/IKKe protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human IKBKE / IKKE protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product IKBKE Protein
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Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase epsilon (IKBKE) (AA 1-716) (Active) protein (GST tag)
IKBKE Origin: Human Host: Insect cells (Sf21) Recombinant SDS, Func Active
Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase epsilon (IKBKE) (AA 1-716) (Active) protein (His-GST)IKBKE Origin: Human Host: Insect cells (Sf9) Recombinant SDS, Func Active
Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase epsilon (IKBKE) (AA 541-640) protein (GST tag)IKBKE Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase epsilon (IKBKE) (AA 1-716) protein (Strep Tag)Crystallography grade IKBKE Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, ELISA, WB
Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase epsilon (IKBKE) (AA 1-717) protein (Strep Tag)Crystallography grade IKBKE Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, ELISA, WB
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- IKKi/IKKe (IKBKE) (Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase epsilon (IKBKE))
- Alternative Name
- Ikbke,ikke (IKBKE Products)
- Synonyms
- zgc:100844 Protein, IKBKE Protein, MGC130907 Protein, IKK-E Protein, IKK-i Protein, IKKE Protein, IKKI Protein, AW558201 Protein, IKKepsilon Protein, Ikki Protein, inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon Protein, inhibitor of nuclear factor kappa B kinase subunit epsilon Protein, inhibitor of nuclear factor kappa B kinase subunit epsilon L homeolog Protein, inhibitor of kappaB kinase epsilon Protein, IKBKE Protein, ikbke Protein, ikbke.L Protein, Ikbke Protein
- Background
- IKBKE is a noncanonical I-kappa-B (see MIM 164008) kinase (IKK) that is essential for regulating antiviral signaling pathways. IKBKE has also been identified as a breast cancer (MIM 114480) oncogene and is amplified and overexpressed in over 30 % of breast carcinomas and breast cancer cell lines (Hutti et al., 2009 [PubMed 19481526]).[supplied by OMIM, Oct 2009].
- Molecular Weight
- 80.3 kDa
- NCBI Accession
- NP_054721
- Pathways
- TLR Signaling, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades
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