LCK Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)
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- Target See all LCK Proteins
- LCK (Lymphocyte-Specific Protein tyrosine Kinase (LCK))
- Protein Type
- Recombinant
- Protein Characteristics
- Transcript Variant 2
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This LCK protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human LCK (transcript variant 2) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product LCK Protein
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Lymphocyte-Specific Protein tyrosine Kinase (LCK) (AA 1-509) (Active) protein (His-GST)
LCK Origin: Human Host: Insect cells (Sf9) Recombinant SDS, Func Active
Lymphocyte-Specific Protein tyrosine Kinase (LCK) (AA 1-539) protein (GST tag)LCK Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
Lymphocyte-Specific Protein tyrosine Kinase (LCK) (AA 1-100) protein (GST tag)LCK Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
Lymphocyte-Specific Protein tyrosine Kinase (LCK) (AA 2-509) protein (His tag)Crystallography grade LCK Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS, Crys
Lymphocyte-Specific Protein tyrosine Kinase (LCK) (AA 2-509) protein (His tag)Crystallography grade LCK Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS, Crys
Lymphocyte-Specific Protein tyrosine Kinase (LCK) (AA 1-539), (Isoform 3) protein (His-SUMO Tag)LCK Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % SDS
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- LCK (Lymphocyte-Specific Protein tyrosine Kinase (LCK))
- Alternative Name
- Lck (LCK Products)
- Synonyms
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zgc:136695 Protein, LCK Protein, Hck-3 Protein, Lsk Protein, Lskt Protein, p56
Protein, p56Lck Protein, LSK Protein, YT16 Protein, p56lck Protein, pp58lck Protein, P56LCK Protein, tkl Protein, Lck1 Protein, Lcktkr Protein, LCK proto-oncogene, Src family tyrosine kinase Protein, lymphocyte protein tyrosine kinase Protein, lck Protein, LCK Protein, Lck Protein - Background
- This gene is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein is a key signaling molecule in the selection and maturation of developing T-cells. It contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to the plasma membrane and pericentrosomal vesicles, and binds to cell surface receptors, including CD4 and CD8, and other signaling molecules. Multiple alternatively spliced variants encoding different isoforms have been described.
- Molecular Weight
- 57.8 kDa
- NCBI Accession
- NP_005347
- Pathways
- TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Transition Metal Ion Homeostasis, Positive Regulation of Endopeptidase Activity, CXCR4-mediated Signaling Events, Thromboxane A2 Receptor Signaling
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