LRRFIP2 Protein (Transcript Variant 3) (Myc-DYKDDDDK Tag)
LRRFIP2
Origin: Human
Host: HEK-293 Cells
Recombinant
> 80 % as determined by SDS-PAGE and Coomassie blue staining
AbP, STD
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- Target See all LRRFIP2 Proteins
- LRRFIP2 (Leucine Rich Repeat (In FLII) Interacting Protein 2 (LRRFIP2))
- Protein Type
- Recombinant
- Protein Characteristics
- Transcript Variant 3
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This LRRFIP2 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human LRRFIP2 (transcript variant 3) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product LRRFIP2 Protein
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Leucine Rich Repeat (In FLII) Interacting Protein 2 (LRRFIP2) (AA 1-400) protein (GST tag)
LRRFIP2 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- LRRFIP2 (Leucine Rich Repeat (In FLII) Interacting Protein 2 (LRRFIP2))
- Alternative Name
- Lrrfip2 (LRRFIP2 Products)
- Synonyms
- HUFI-2 Protein, 5133400F20Rik Protein, AI850587 Protein, wu:fj34c02 Protein, zgc:113956 Protein, zgc:63771 Protein, LRR binding FLII interacting protein 2 Protein, leucine rich repeat (in FLII) interacting protein 2 Protein, leucine rich repeat (in FLII) interacting protein 2 L homeolog Protein, LRRFIP2 Protein, Lrrfip2 Protein, lrrfip2 Protein, lrrfip2.L Protein
- Background
- The protein encoded by this gene, along with MYD88, binds to the cytosolic tail of toll-like receptor 4 (TLR4), which results in activation of nuclear factor kappa B signaling. The ubiquitin-like protein FAT10 prevents the interaction of the encoded protein and TLR4, thereby inactivating the nuclear factor kappa B signaling pathway. In addition, this protein can downregulate the NLRP3 inflammasome by recruiting the caspase-1 inhibitor Flightless-I to the inflammasome complex.
- Molecular Weight
- 48.1 kDa
- NCBI Accession
- NP_001127841
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