Quick Overview for MAP2K6 Protein (Myc-DYKDDDDK Tag) (ABIN2725394)
Target
See all MAP2K6 ProteinsProtein Type
Origin
Source
Application
Purity
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Purification tag / Conjugate
- This MAP2K6 protein is labelled with Myc-DYKDDDDK Tag.
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Characteristics
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- Recombinant human MAP2K6 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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Mitogen-Activated Protein Kinase Kinase 6 (MAP2K6) (AA 6-334) protein (His tag)
MAP2K6 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
Mitogen-Activated Protein Kinase Kinase 6 (MAP2K6) (Active) protein (His-GST)MAP2K6 Origin: Human Host: Baculovirus infected Insect Cells Recombinant > 88 % as determined by reducing SDS-PAGE. Active
Mitogen-Activated Protein Kinase Kinase 6 (MAP2K6) protein (His-GST)MAP2K6 Origin: Human Host: Baculovirus infected Insect Cells Recombinant > 80 % as determined by reducing SDS-PAGE.
Mitogen-Activated Protein Kinase Kinase 6 (MAP2K6) (AA 1-334) protein (GST tag)MAP2K6 Origin: Human Host: Wheat germ Recombinant AP, AA, ELISA, WB
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Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Comment
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Storage
- -80 °C
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Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- MAP2K6 (Mitogen-Activated Protein Kinase Kinase 6 (MAP2K6))
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Alternative Name
- Map2k6
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Background
- This gene encodes a member of the dual specificity protein kinase family, which functions as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein phosphorylates and activates p38 MAP kinase in response to inflammatory cytokines or environmental stress. As an essential component of p38 MAP kinase mediated signal transduction pathway, this gene is involved in many cellular processes such as stress induced cell cycle arrest, transcription activation and apoptosis.
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Molecular Weight
- 37.3 kDa
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NCBI Accession
- NP_002749
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Pathways
- MAPK Signaling, TLR Signaling, Activation of Innate immune Response, Regulation of Muscle Cell Differentiation, Toll-Like Receptors Cascades
Target
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