MC2R Protein (Myc-DYKDDDDK Tag)

Catalog No. ABIN2725592

Product Details

Target: MC2R (Melanocortin 2 Receptor (Adrenocorticotropic Hormone) (MC2R))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This MC2R protein is labelled with Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human MC2-R protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: MC2R (Melanocortin 2 Receptor (Adrenocorticotropic Hormone) (MC2R))

Alternative Name: Mc2-R (MC2R Products)

Synonyms: ACTHR Protein, ACTH-R Protein, MC2-R Protein, MC2R Protein, MC2 Protein, melanocortin 2 receptor Protein, MC2R Protein, Mc2r Protein, mc2r Protein

Background: MC2R encodes one member of the five-member G-protein associated melanocortin receptor family. Melanocortins (melanocyte-stimulating hormones and adrenocorticotropic hormone) are peptides derived from pro-opiomelanocortin (POMC). MC2R is selectively activated by adrenocorticotropic hormone, whereas the other four melanocortin receptors recognize a variety of melanocortin ligands. Mutations in MC2R can result in familial glucocorticoid deficiency. Alternate transcript variants have been found for this gene.

Molecular Weight: 33.7 kDa

NCBI Accession: NP_000520

Pathways: cAMP Metabolic Process