Mre11 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

Catalog No. ABIN2726317

Product Details

Target: Mre11 (MRE11A) (MRE11 Meiotic Recombination 11 Homolog A (S. Cerevisiae) (MRE11A))

Protein Type: Recombinant

Protein Characteristics: Transcript Variant 1

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This Mre11 protein is labelled with Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human MRE11 (transcript variant 1) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: Mre11 (MRE11A) (MRE11 Meiotic Recombination 11 Homolog A (S. Cerevisiae) (MRE11A))

Alternative Name: Mre11 (MRE11A Products)

Synonyms: wu:faa63d12 Protein, zgc:64018 Protein, Mre11 Protein, Mre11b Protein, ATLD Protein, HNGS1 Protein, MRE11 Protein, MRE11B Protein, MRE11 homolog A, double strand break repair nuclease Protein, MRE11 homolog, double strand break repair nuclease Protein, MRE11A homolog A, double strand break repair nuclease Protein, mre11a Protein, MRE11 Protein, Mre11a Protein

Background: This gene encodes a nuclear protein involved in homologous recombination, telomere length maintenance, and DNA double-strand break repair. By itself, the protein has 3&apos to 5&apos exonuclease activity and endonuclease activity. The protein forms a complex with the RAD50 homolog this complex is required for nonhomologous joining of DNA ends and possesses increased single-stranded DNA endonuclease and 3&apos to 5&apos exonuclease activities. In conjunction with a DNA ligase, this protein promotes the joining of noncomplementary ends in vitro using short homologies near the ends of the DNA fragments. This gene has a pseudogene on chromosome 3. Alternative splicing of this gene results in two transcript variants encoding different isoforms.

Molecular Weight: 80.4 kDa

NCBI Accession: NP_005582

Pathways: DNA Damage Repair