MSH2 Protein (Myc-DYKDDDDK Tag)
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- Target See all MSH2 Proteins
- MSH2 (Mismatch Repair Protein 2 (MSH2))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This MSH2 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human MSH2 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product MSH2 Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- MSH2 (Mismatch Repair Protein 2 (MSH2))
- Alternative Name
- Msh2 (MSH2 Products)
- Synonyms
- COCA1 Protein, FCC1 Protein, HNPCC Protein, HNPCC1 Protein, LCFS2 Protein, AI788990 Protein, wu:fc06b02 Protein, wu:fc13e09 Protein, zgc:55333 Protein, ATMSH2 Protein, MUTS homolog 2 Protein, msh2 Protein, mutS homolog 2 Protein, mutS homolog 2 (E. coli) Protein, MUTS homolog 2 Protein, mutS homolog 2 L homeolog Protein, MutS protein homolog 2 Protein, MSH2 Protein, Msh2 Protein, msh2 Protein, msh2.L Protein
- Background
- This locus is frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). When cloned, it was discovered to be a human homolog of the E. coli mismatch repair gene mutS, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. Two transcript variants encoding different isoforms have been found for this gene.
- Molecular Weight
- 104.6 kDa
- NCBI Accession
- NP_000242
- Pathways
- DNA Damage Repair, Production of Molecular Mediator of Immune Response
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