MTHFR Protein (Myc-DYKDDDDK Tag)
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- Target See all MTHFR Proteins
- MTHFR (Methylenetetrahydrofolate Reductase (NAD(P)H) (MTHFR))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This MTHFR protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human MTHFR protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product MTHFR Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- MTHFR (Methylenetetrahydrofolate Reductase (NAD(P)H) (MTHFR))
- Alternative Name
- Mthfr (MTHFR Products)
- Synonyms
- DDBDRAFT_0204686 Protein, DDBDRAFT_0230137 Protein, DDB_0204686 Protein, DDB_0230137 Protein, AI323986 Protein, methylenetetrahydrofolate reductase (NAD(P)H) L homeolog Protein, methylenetetrahydrofolate reductase Protein, methylenetetrahydrofolate reductase (NAD(P)H) Protein, 5,10-methylenetetrahydrofolate reductase Protein, mthfr.L Protein, MTHFR Protein, mthfr Protein, metF Protein, DDB_G0279137 Protein, Mthfr Protein
- Background
- The protein encoded by this gene catalyzes the conversion of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate, a co-substrate for homocysteine remethylation to methionine. Genetic variation in this gene influences susceptibility to occlusive vascular disease, neural tube defects, colon cancer and acute leukemia, and mutations in this gene are associated with methylenetetrahydrofolate reductase deficiency.[provided by RefSeq, Oct 2009].
- Molecular Weight
- 74.4 kDa
- NCBI Accession
- NP_005948
- Pathways
- Methionine Biosynthetic Process
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