PDE10A Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)

Catalog No. ABIN2728474

This Recombinant PDE10A protein is expressed in HEK-293 Cells.

Quick Overview for PDE10A Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag) (ABIN2728474)

Target: PDE10A (phosphodiesterase 10A (PDE10A))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Application: Antibody Production (AbP), Standard (STD)

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Product Details

Protein Characteristics: Transcript Variant 2

Purification tag / Conjugate: This PDE10A protein is labelled with Myc-DYKDDDDK Tag.

Characteristics:

• Recombinant human PDE10A (transcript variant 2) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: PDE10A (phosphodiesterase 10A (PDE10A))

Alternative Name: Pde10a

Background: The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase family. It plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides. This protein can hydrolyze both cAMP and cGMP to the corresponding nucleoside 5&apos monophosphate, but has higher affinity for cAMP, and is more efficient with cAMP as substrate. Alternatively spliced transcript variants have been described for this gene.

Molecular Weight: 88.2 kDa

NCBI Accession: NP_006652

Pathways: cAMP Metabolic Process