PICK1 Protein (Transcript Variant 3) (Myc-DYKDDDDK Tag)
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- Target See all PICK1 Proteins
- PICK1 (Protein Interacting With Protein Kinase C, alpha 1 (PICK1))
- Protein Type
- Recombinant
- Protein Characteristics
- Transcript Variant 3
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This PICK1 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human PICK1 (transcript variant 3) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product PICK1 Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- PICK1 (Protein Interacting With Protein Kinase C, alpha 1 (PICK1))
- Alternative Name
- Pick1 (PICK1 Products)
- Synonyms
- PICK Protein, PRKCABP Protein, Prkcabp Protein, prkcabp Protein, MGC131295 Protein, PICK1 Protein, DKFZp470L2127 Protein, protein interacting with PRKCA 1 Protein, protein interacting with C kinase 1 Protein, protein interacting with PRKCA 1 L homeolog Protein, PICK1 Protein, Pick1 Protein, pick1 Protein, pick1.L Protein
- Background
- The protein encoded by this gene contains a PDZ domain, through which it interacts with protein kinase C, alpha (PRKCA). This protein may function as an adaptor that binds to and organizes the subcellular localization of a variety of membrane proteins. It has been shown to interact with multiple glutamate receptor subtypes, monoamine plasma membrane transporters, as well as non-voltage gated sodium channels, and may target PRKCA to these membrane proteins and thus regulate their distribution and function. This protein has also been found to act as an anchoring protein that specifically targets PRKCA to mitochondria in a ligand-specific manner. Three transcript variants encoding the same protein have been found for this gene.
- Molecular Weight
- 46.4 kDa
- NCBI Accession
- NP_001034673
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