PLAGL1 Protein (His tag)
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- Target See all PLAGL1 Proteins
- PLAGL1 (Pleiomorphic Adenoma Gene-Like 1 (PLAGL1))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This PLAGL1 protein is labelled with His tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human PLAGL1 (N-term HIS tag, transcript variant 1) protein expressed in E. coli.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product PLAGL1 Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the N-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris, pH 8.0, 150 mM NaCl, 10 % glycerol, 1 % Sarkosyl. Store at -80C. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- PLAGL1 (Pleiomorphic Adenoma Gene-Like 1 (PLAGL1))
- Alternative Name
- Plagl1 (PLAGL1 Products)
- Synonyms
- PLAGL1 Protein, LOT1 Protein, ZAC Protein, ZAC1 Protein, Lot1 Protein, Zac1 Protein, PLAG1 like zinc finger 1 Protein, uncharacterized LOC100350914 Protein, pleiomorphic adenoma gene-like 1 Protein, PLAGL1 Protein, LOC100350914 Protein, Plagl1 Protein
- Background
- This gene encodes a C2H2 zinc finger protein that functions as a suppressor of cell growth. This gene is often deleted or methylated and silenced in cancer cells. In addition, overexpression of this gene during fetal development is thought to be the causal factor for transient neonatal diabetes mellitus (TNDM). Alternative splicing and the use of alternative promoters results in multiple transcript variants encoding two different protein isoforms. The P1 downstream promoter of this gene is imprinted, with preferential expression from the paternal allele in many tissues.
- Molecular Weight
- 44.5 kDa
- NCBI Accession
- NP_002647
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