PNKP Protein (Myc-DYKDDDDK Tag)

Catalog No. ABIN2729231

Recombinant PNKP protein expressed in HEK-293 Cells.

Quick Overview for PNKP Protein (Myc-DYKDDDDK Tag) (ABIN2729231)

Target: PNKP (Polynucleotide Kinase 3'-Phosphatase (PNKP))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Application: Antibody Production (AbP), Standard (STD)

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Product Details

Purification tag / Conjugate: This PNKP protein is labelled with Myc-DYKDDDDK Tag.

Characteristics:

• Recombinant human PNKP protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: PNKP (Polynucleotide Kinase 3'-Phosphatase (PNKP))

Alternative Name: Pnkp

Background: This locus represents a gene involved in DNA repair. In response to ionizing radiation or oxidative damage, the protein encoded by this locus catalyzes 5' phosphorylation and 3' dephosphorylation of nucleic acids. Mutations at this locus have been associated with microcephaly, seizures, and developmental delay.[provided by RefSeq, Sep 2010].

Molecular Weight: 56.9 kDa

NCBI Accession: NP_009185

Pathways: DNA Damage Repair, Nucleotide Phosphorylation