PPP1CA Protein (His tag)

Catalog No. ABIN2729463

Product Details

Target: PPP1CA (Protein Phosphatase 1, Catalytic Subunit, alpha Isoform (PPP1CA))

Protein Type: Recombinant

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This PPP1CA protein is labelled with His tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human PPP1CA (full length, N-term HIS tag, transcript variant 1) protein expressed in E. coli.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the N-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris, pH 8.0, 150 mM NaCl, 10 % glycerol, 1 % Sarkosyl.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: PPP1CA (Protein Phosphatase 1, Catalytic Subunit, alpha Isoform (PPP1CA))

Alternative Name: Ppp1ca (PPP1CA Products)

Synonyms: PP-1A Protein, PP1A Protein, PP1alpha Protein, PPP1A Protein, Ppp1c Protein, dism2 Protein, ppp1a Protein, wu:fc04c08 Protein, wu:fc09b07 Protein, wu:fc30g11 Protein, wu:fe05h08 Protein, zgc:85729 Protein, Ppp1ca Protein, fb18b03 Protein, fd20h04 Protein, wu:fb18b03 Protein, wu:fd20h04 Protein, wu:fl22a03 Protein, zgc:55744 Protein, zgc:76940 Protein, protein phosphatase 1 catalytic subunit alpha Protein, protein phosphatase 1, catalytic subunit, alpha isoform Protein, protein phosphatase 1, catalytic subunit, alpha isozyme L homeolog Protein, protein phosphatase 1, catalytic subunit, alpha isozyme Protein, protein phosphatase 1, catalytic subunit, alpha isozyme a Protein, protein phosphatase 1, catalytic subunit, alpha isozyme b Protein, PPP1CA Protein, Ppp1ca Protein, ppp1ca.L Protein, ppp1ca Protein, ppp1caa Protein, ppp1cab Protein

Background: The protein encoded by this gene is one of the three catalytic subunits of protein phosphatase 1 (PP1). PP1 is a serine/threonine specific protein phosphatase known to be involved in the regulation of a variety of cellular processes, such as cell division, glycogen metabolism, muscle contractility, protein synthesis, and HIV-1 viral transcription. Increased PP1 activity has been observed in the end stage of heart failure. Studies in both human and mice suggest that PP1 is an important regulator of cardiac function. Mouse studies also suggest that PP1 functions as a suppressor of learning and memory. Three alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Molecular Weight: 37.3 kDa

NCBI Accession: NP_002699

Pathways: M Phase, Cellular Glucan Metabolic Process, Regulation of Carbohydrate Metabolic Process, Lipid Metabolism