PPP2R4 Protein (Transcript Variant 3) (Myc-DYKDDDDK Tag)

Catalog No. ABIN2729491

Product Details

Target: PPP2R4 (Protein Phosphatase 2A Activator, Regulatory Subunit 4 (PPP2R4))

Protein Type: Recombinant

Protein Characteristics: Transcript Variant 3

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This PPP2R4 protein is labelled with Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human PPP2R4 / PTPA (transcript variant 3) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: PPP2R4 (Protein Phosphatase 2A Activator, Regulatory Subunit 4 (PPP2R4))

Alternative Name: Ppp2r4,ptpa (PPP2R4 Products)

Synonyms: PP2A Protein, PR53 Protein, PTPA Protein, 2610042B21Rik Protein, C77440 Protein, N28142 Protein, PTPRA Protein, Ppp2r4 Protein, fc23d07 Protein, ppp2r4 Protein, wu:fc23d07 Protein, zgc:92766 Protein, pp2a Protein, ppp2r4.L Protein, pr53 Protein, ptpa Protein, protein phosphatase 2 phosphatase activator Protein, protein phosphatase 2 protein activator Protein, protein phosphatase 2 phosphatase activator L homeolog Protein, PTPA Protein, Ptpa Protein, ptpa Protein, ptpa.L Protein

Background: Protein phosphatase 2A is one of the four major Ser/Thr phosphatases and is implicated in the negative control of cell growth and division. Protein phosphatase 2A holoenzymes are heterotrimeric proteins composed of a structural subunit A, a catalytic subunit C, and a regulatory subunit B. The regulatory subunit is encoded by a diverse set of genes that have been grouped into the B/PR55, B&apos/PR61, and B&apos&apos/PR72 families. These different regulatory subunits confer distinct enzymatic specificities and intracellular localizations to the holozenzyme. The product of this gene belongs to the B&apos family. This gene encodes a specific phosphotyrosyl phosphatase activator of the dimeric form of protein phosphatase 2A. Alternative splicing results in multiple transcript variants encoding different isoforms.

Molecular Weight: 36.6 kDa

NCBI Accession: NP_066954

Pathways: PI3K-Akt Signaling, M Phase, Hepatitis C, Toll-Like Receptors Cascades