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PTGER4 Protein (Myc-DYKDDDDK Tag)

PTGER4 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2730063
  • Target See all PTGER4 Proteins
    PTGER4 (Prostaglandin E Receptor 4 (Subtype EP4) (PTGER4))
    Protein Type
    Recombinant
    Origin
    • 8
    • 2
    Human
    Source
    • 3
    • 3
    • 2
    • 2
    HEK-293 Cells
    Purification tag / Conjugate
    This PTGER4 protein is labelled with Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human PTGER4 protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product PTGER4 Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    PTGER4 (Prostaglandin E Receptor 4 (Subtype EP4) (PTGER4))
    Alternative Name
    Ptger4 (PTGER4 Products)
    Synonyms
    EP4 Protein, PGE2R-EP4 Protein, ptger4 Protein, ptger4l Protein, PTGER4 Protein, EP4R Protein, Ptgerep4 Protein, Ptger Protein, ep4 Protein, prostaglandin E receptor 4 Protein, prostaglandin E receptor 4 (subtype EP4) Protein, prostaglandin E receptor 4 (subtype EP4) a Protein, prostaglandin E receptor 4 subtype EP4 Protein, PTGER4 Protein, ptger4a Protein, ptger4 Protein, Ptger4 Protein
    Background
    The protein encoded by this gene is a member of the G-protein coupled receptor family. This protein is one of four receptors identified for prostaglandin E2 (PGE2). This receptor can activate T-cell factor signaling. It has been shown to mediate PGE2 induced expression of early growth response 1 (EGR1), regulate the level and stability of cyclooxygenase-2 mRNA, and lead to the phosphorylation of glycogen synthase kinase-3. Knockout studies in mice suggest that this receptor may be involved in the neonatal adaptation of circulatory system, osteoporosis, as well as initiation of skin immune responses.
    Molecular Weight
    52.9 kDa
    NCBI Accession
    NP_000949
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