PTGER4 Protein (Fc Tag)

Catalog No. ABIN6964314

Product Details

Target: PTGER4 (Prostaglandin E Receptor 4 (Subtype EP4) (PTGER4))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This PTGER4 protein is labelled with Fc Tag.

Purpose: Recombinant Human PTGER4 Protein with C-terminal human Fc tag

Specificity: PTGER4 (Met1-Ser19) hFc (Glu99-Ala330)

Characteristics: Extracellular Domain Protein

Purification: affinity purification

Purity: The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Reconstitute with deionized water

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Preservative: Without preservative

Storage: -20 °C,-80 °C

Storage Comment: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Expiry Date: 12 months

Target Details

Target: PTGER4 (Prostaglandin E Receptor 4 (Subtype EP4) (PTGER4))

Alternative Name: PTGER4 (PTGER4 Products)

Synonyms: EP4 Protein, PGE2R-EP4 Protein, ptger4 Protein, ptger4l Protein, PTGER4 Protein, EP4R Protein, Ptgerep4 Protein, Ptger Protein, ep4 Protein, prostaglandin E receptor 4 Protein, prostaglandin E receptor 4 (subtype EP4) Protein, prostaglandin E receptor 4 (subtype EP4) a Protein, prostaglandin E receptor 4 subtype EP4 Protein, PTGER4 Protein, ptger4a Protein, ptger4 Protein, Ptger4 Protein

Background: Synonymes: EP4, EP4R
Description: The protein encoded by this gene is a member of the G-protein coupled receptor family. This protein is one of four receptors identified for prostaglandin E2 (PGE2). This receptor can activate T-cell factor signaling. It has been shown to mediate PGE2 induced expression of early growth response 1 (EGR1), regulate the level and stability of cyclooxygenase-2 mRNA, and lead to the phosphorylation of glycogen synthase kinase-3. Knockout studies in mice suggest that this receptor may be involved in the neonatal adaptation of circulatory system, osteoporosis, as well as initiation of skin immune responses. [provided by RefSeq, Jul 2008]

Molecular Weight: predicted molecular mass of 28.1 kDa after removal of the signal peptide. The apparent molecular mass of PTGER4-hFc is 35-55 kDa due to glycosylation.

UniProt: P35408