PTPN7 Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)
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- Target See all PTPN7 Proteins
- PTPN7 (Protein tyrosine Phosphatase, Non-Receptor Type 7 (PTPN7))
- Protein Type
- Recombinant
- Protein Characteristics
- Transcript Variant 2
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This PTPN7 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human PTPN7 / HEPTP (transcript variant 2) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product PTPN7 Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- PTPN7 (Protein tyrosine Phosphatase, Non-Receptor Type 7 (PTPN7))
- Alternative Name
- Ptpn7,heptp (PTPN7 Products)
- Synonyms
- BPTP-4 Protein, HEPTP Protein, LC-PTP Protein, LPTP Protein, PTPNI Protein, C920001D21Rik Protein, Heptp Protein, Lcptp Protein, protein tyrosine phosphatase, non-receptor type 7 Protein, PTPN7 Protein, Ptpn7 Protein
- Background
- The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This gene is preferentially expressed in a variety of hematopoietic cells, and is an early response gene in lymphokine stimulated cells. The non-catalytic N-terminus of this PTP can interact with MAP kinases and suppress the MAP kinase activities. This PTP was shown to be involved in the regulation of T cell antigen receptor (TCR) signaling, which was thought to function through dephosphorylating the molecules related to MAP kinase pathway. Multiple alternatively spliced transcript variants have been found for this gene.
- Molecular Weight
- 44.8 kDa
- NCBI Accession
- NP_542155
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