PUM1 Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)
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- Target See all PUM1 Proteins
- PUM1 (Pumilio Homolog 1 (PUM1))
- Protein Type
- Recombinant
- Protein Characteristics
- Transcript Variant 2
- Origin
- Human
- Source
- HEK-293 Cells
- Purification tag / Conjugate
- This PUM1 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human Pumilio 1 / PUM1 (transcript variant 2) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- PUM1 (Pumilio Homolog 1 (PUM1))
- Alternative Name
- Pumilio 1,pum1 (PUM1 Products)
- Synonyms
- fb96a03 Protein, pumilio1 Protein, si:ch211-285e16.1 Protein, wu:fb96a03 Protein, wu:fb96a08 Protein, zgc:63671 Protein, PUM1 Protein, DKFZp459K0627 Protein, AA517475 Protein, Pumm Protein, mKIAA0099 Protein, HSPUM Protein, PUMH Protein, PUMH1 Protein, PUML1 Protein, pumilio RNA-binding family member 1 Protein, pumilio RNA binding family member 1 Protein, pum1 Protein, PUM1 Protein, Pum1 Protein
- Background
- This gene encodes a member of the PUF family, evolutionarily conserved RNA-binding proteins related to the Pumilio proteins of Drosophila and the fem-3 mRNA binding factor proteins of C. elegans. The encoded protein contains a sequence-specific RNA binding domain comprised of eight repeats and N- and C-terminal flanking regions, and serves as a translational regulator of specific mRNAs by binding to their 3' untranslated regions. The evolutionarily conserved function of the encoded protein in invertebrates and lower vertebrates suggests that the human protein may be involved in translational regulation of embryogenesis, and cell development and differentiation. Alternatively spliced transcript variants encoding different isoforms have been described.
- Molecular Weight
- 126.3 kDa
- NCBI Accession
- NP_055491
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