PC Protein (Transcript Variant 3) (Myc-DYKDDDDK Tag)
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- Target See all PC Proteins
- PC (Pyruvate Carboxylase (PC))
- Protein Type
- Recombinant
- Protein Characteristics
- Transcript Variant 3
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This PC protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human Pyruvic carboxylase (PC) (transcript variant 3) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product PC Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- PC (Pyruvate Carboxylase (PC))
- Alternative Name
- Pyruvic Carboxylase (Pc) (PC Products)
- Synonyms
- BcDNA Protein, BcDNA:GH06348 Protein, Dmel\\CG1516 Protein, PC Protein, pyc Protein, wu:fb82g08 Protein, wu:fj85g01 Protein, PCX Protein, BA4157 Protein, Pc Protein, Pcb Protein, PCB Protein, Pcx Protein, Pyruvate carboxylase Protein, pyruvate carboxylase b Protein, PYruvate Carboxylase Protein, pyruvate carboxylase Protein, pyruvate carboxylase Pyr1 Protein, PCB Protein, pcxb Protein, pyc-1 Protein, PC Protein, pyc Protein, pyr1 Protein, CNF00650 Protein, PYC1 Protein, Ndas_1152 Protein, Ilyop_2503 Protein, Calni_0495 Protein, Ftrac_1004 Protein, Plabr_3574 Protein, Sgly_2936 Protein, Celly_0558 Protein, Hipma_0131 Protein, Halhy_1567 Protein, Mesop_1269 Protein, Pcx Protein, Pc Protein
- Background
- This gene encodes pyruvate carboxylase, which requires biotin and ATP to catalyse the carboxylation of pyruvate to oxaloacetate. The active enzyme is a homotetramer arranged in a tetrahedron which is located exclusively in the mitochondrial matrix. Pyruvate carboxylase is involved in gluconeogenesis, lipogenesis, insulin secretion and synthesis of the neurotransmitter glutamate. Mutations in this gene have been associated with pyruvate carboxylase deficiency. Alternatively spliced transcript variants with different 5' UTRs, but encoding the same protein, have been found for this gene.
- Molecular Weight
- 127.3 kDa
- NCBI Accession
- NP_001035806
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