RNASEH2B Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)
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- Target See all RNASEH2B Proteins
- RNASEH2B (Ribonuclease H2, Subunit B (RNASEH2B))
- Protein Type
- Recombinant
- Protein Characteristics
- Transcript Variant 2
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This RNASEH2B protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human Ribonuclease H2, subunit B (RNASEH2B), transcript variant 2 (transcript variant 2) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- RNASEH2B (Ribonuclease H2, Subunit B (RNASEH2B))
- Abstract
- RNASEH2B Products
- Synonyms
- AGS2 Protein, DLEU8 Protein, 1110019N06Rik Protein, 2610207P08Rik Protein, Dleu8 Protein, ribonuclease H2 subunit B Protein, ribonuclease H2, subunit B Protein, ribonuclease H2 subunit B L homeolog Protein, RNASEH2B Protein, Rnaseh2b Protein, rnaseh2b.L Protein
- Background
- RNase H2 is composed of a single catalytic subunit (A) and two non-catalytic subunits (B and C) and specifically degrades the RNA of RNA:DNA hybrids. The protein encoded by this gene is the non-catalytic B subunit of RNase H2, which is thought to play a role in DNA replication. Multiple transcript variants encoding different isoforms have been found for this gene. Defects in this gene are a cause of Aicardi-Goutieres syndrome type 2 (AGS2).
- Molecular Weight
- 28.8 kDa
- NCBI Accession
- NP_001135751
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