RNASEH2A Protein (Myc-DYKDDDDK Tag)
-
- Target See all RNASEH2A Proteins
- RNASEH2A (Ribonuclease H2, Subunit A (RNASEH2A))
- Protein Type
- Recombinant
-
Origin
- Human
-
Source
- HEK-293 Cells
- Purification tag / Conjugate
- This RNASEH2A protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
-
- Recombinant human RNASEH2A protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product RNASEH2A Protein
-
-
- Application Notes
-
Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
-
The tag is located at the C-terminal.
- Restrictions
- For Research Use only
-
- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
-
- Target
- RNASEH2A (Ribonuclease H2, Subunit A (RNASEH2A))
- Alternative Name
- Rnaseh2a (RNASEH2A Products)
- Synonyms
- 2400006P09Rik Protein, RNASEHI Protein, RNHIA Protein, RNHL Protein, zgc:56307 Protein, AGS4 Protein, JUNB Protein, ribonuclease H2 subunit A Protein, ribonuclease H2, large subunit Protein, ribonuclease H2, subunit A Protein, ribonuclease H2 subunit A L homeolog Protein, rnaseh2a Protein, RNASEH2A Protein, Rnaseh2a Protein, rnaseh2a.L Protein
- Background
- The protein encoded by this gene is a component of the heterotrimeric type II ribonuclease H enzyme (RNAseH2). RNAseH2 is the major source of ribonuclease H activity in mammalian cells and endonucleolytically cleaves ribonucleotides. It is predicted to remove Okazaki fragment RNA primers during lagging strand DNA synthesis and to excise single ribonucleotides from DNA-DNA duplexes. Mutations in this gene cause Aicardi-Goutieres Syndrome (AGS), a an autosomal recessive neurological disorder characterized by progressive microcephaly and psychomotor retardation, intracranial calcifications, elevated levels of interferon-alpha and white blood cells in the cerebrospinal fluid.[provided by RefSeq, Aug 2009].
- Molecular Weight
- 33.2 kDa
- NCBI Accession
- NP_006388
-