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FIG4 Protein (Myc-DYKDDDDK Tag)

FIG4 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2731347
  • Target See all FIG4 Proteins
    FIG4 (FIG4 Homolog, SAC1 Lipid Phosphatase Domain Containing (FIG4))
    Protein Type
    Recombinant
    Origin
    • 2
    • 1
    Human
    Source
    • 2
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This FIG4 protein is labelled with Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human SAC3 protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product FIG4 Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    FIG4 (FIG4 Homolog, SAC1 Lipid Phosphatase Domain Containing (FIG4))
    Alternative Name
    Sac3 (FIG4 Products)
    Synonyms
    A530089I17Rik Protein, AI326867 Protein, Sac3 Protein, ALS11 Protein, CMT4J Protein, KIAA0274 Protein, SAC3 Protein, YVS Protein, dJ249I4.1 Protein, Kiaa0274 Protein, RGD1311375 Protein, FIG4 phosphoinositide 5-phosphatase Protein, Fig4 Protein, FIG4 Protein
    Background
    The protein encoded by this gene belongs to the SAC domain-containing protein gene family. The SAC domain, approximately 400 amino acids in length and consisting of seven conserved motifs, has been shown to possess phosphoinositide phosphatase activity. The yeast homolog, Sac1p, is involved in the regulation of various phosphoinositides, and affects diverse cellular functions such as actin cytoskeleton organization, Golgi function, and maintenance of vacuole morphology. Membrane-bound phosphoinositides function as signaling molecules and play a key role in vesicle trafficking in eukaryotic cells. Mutations in this gene have been associated with Charcot-Marie-Tooth disease, type 4J.
    Molecular Weight
    103.5 kDa
    NCBI Accession
    NP_055660
    Pathways
    Inositol Metabolic Process
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