FIG4 Protein (Myc-DYKDDDDK Tag)
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- Target See all FIG4 Proteins
- FIG4 (FIG4 Homolog, SAC1 Lipid Phosphatase Domain Containing (FIG4))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This FIG4 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human SAC3 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product FIG4 Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- FIG4 (FIG4 Homolog, SAC1 Lipid Phosphatase Domain Containing (FIG4))
- Alternative Name
- Sac3 (FIG4 Products)
- Synonyms
- A530089I17Rik Protein, AI326867 Protein, Sac3 Protein, ALS11 Protein, CMT4J Protein, KIAA0274 Protein, SAC3 Protein, YVS Protein, dJ249I4.1 Protein, Kiaa0274 Protein, RGD1311375 Protein, FIG4 phosphoinositide 5-phosphatase Protein, Fig4 Protein, FIG4 Protein
- Background
- The protein encoded by this gene belongs to the SAC domain-containing protein gene family. The SAC domain, approximately 400 amino acids in length and consisting of seven conserved motifs, has been shown to possess phosphoinositide phosphatase activity. The yeast homolog, Sac1p, is involved in the regulation of various phosphoinositides, and affects diverse cellular functions such as actin cytoskeleton organization, Golgi function, and maintenance of vacuole morphology. Membrane-bound phosphoinositides function as signaling molecules and play a key role in vesicle trafficking in eukaryotic cells. Mutations in this gene have been associated with Charcot-Marie-Tooth disease, type 4J.
- Molecular Weight
- 103.5 kDa
- NCBI Accession
- NP_055660
- Pathways
- Inositol Metabolic Process
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