SART3 Protein (Myc-DYKDDDDK Tag)

Catalog No. ABIN2731408

Product Details

Target: SART3 (Squamous Cell Carcinoma Antigen Recognized By T Cells 3 (SART3))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This SART3 protein is labelled with Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human SART3 / TIP110 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: SART3 (Squamous Cell Carcinoma Antigen Recognized By T Cells 3 (SART3))

Alternative Name: Sart3,tip110 (SART3 Products)

Synonyms: SART3 Protein, DKFZp469J2418 Protein, si:ch211-191d15.4 Protein, wu:fc51h03 Protein, DSAP1 Protein, P100 Protein, RP11-13G14 Protein, TIP110 Protein, p110 Protein, p110(nrb) Protein, AU045857 Protein, mKIAA0156 Protein, squamous cell carcinoma antigen recognized by T-cells 3 Protein, squamous cell carcinoma antigen recognized by T-cells 3 L homeolog Protein, squamous cell carcinoma antigen recognized by T cells 3 Protein, SART3 Protein, sart3 Protein, sart3.L Protein, Sart3 Protein

Background: The protein encoded by this gene is an RNA-binding nuclear protein that is a tumor-rejection antigen. This antigen possesses tumor epitopes capable of inducing HLA-A24-restricted and tumor-specific cytotoxic T lymphocytes in cancer patients and may be useful for specific immunotherapy. This gene product is found to be an important cellular factor for HIV-1 gene expression and viral replication. It also associates transiently with U6 and U4/U6 snRNPs during the recycling phase of the spliceosome cycle. This encoded protein is thought to be involved in the regulation of mRNA splicing.

Molecular Weight: 109.8 kDa

NCBI Accession: NP_055521

Pathways: Ribonucleoprotein Complex Subunit Organization