ORCTL-2/SLC22A18 Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)

Catalog No. ABIN2732154

Product Details

Target: ORCTL-2/SLC22A18 (SLC22A18) (Solute Carrier Family 22 Member 18 (SLC22A18))

Protein Type: Recombinant

Protein Characteristics: Transcript Variant 2

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This ORCTL-2/SLC22A18 protein is labelled with Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human SLC22A18 / ORCTL2 (transcript variant 2) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: ORCTL-2/SLC22A18 (SLC22A18) (Solute Carrier Family 22 Member 18 (SLC22A18))

Alternative Name: Slc22a18,orctl2 (SLC22A18 Products)

Synonyms: MGC123168 Protein, zgc:123168 Protein, BWR1A Protein, BWSCR1A Protein, HET Protein, IMPT1 Protein, ITM Protein, ORCTL2 Protein, SLC22A1L Protein, TSSC5 Protein, p45-BWR1A Protein, AW260131 Protein, Impt1 Protein, Orctl2 Protein, Slc22a1l Protein, solute carrier family 22, member 18 Protein, solute carrier family 22 member 18 Protein, solute carrier family 22 (organic cation transporter), member 18 Protein, slc22a18 Protein, SLC22A18 Protein, Slc22a18 Protein

Background: This gene is one of several tumor-suppressing subtransferable fragments located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. This gene is imprinted, with preferential expression from the maternal allele. Mutations in this gene have been found in Wilms&apos tumor and lung cancer. This protein may act as a transporter of organic cations, and have a role in the transport of chloroquine and quinidine-related compounds in kidney. Several alternatively spliced transcript variants encoding different isoforms have been described.

Molecular Weight: 44.7 kDa

NCBI Accession: NP_899056